Data Requirements Handbook and Supplementary Guidance
The Data Requirements Handbook outlines the data required to support applications for pesticide registration made to the Chemicals Regulation Directorate CRD for approval of agricultural, horticultural and home garden pesticides (also known as plant protection products).
This website (www.pesticides.gov.uk) deals with the approval of agricultural, horticultural and home garden pesticides (also known as plant protection products). Non-agricultural (public hygiene) pesticides and biocides are also the responsibility of CRD. However, information about these products is held on the main HSE website at the following link: http://www.hse.gov.uk/biocides/index.htm (Further Information on this website's current purpose)
All files are in Adobe Acrobat pdf format. For best results you should use the free Acrobat Reader 6.0. Earlier versions may cause problems with links to other pages on this site. Paper copies and details regarding notification of updates are available on request.
These documents contain links to the internet sites of other organisations
CRD is not responsible for the contents or reliability of the linked websites and does not necessarily endorse the views expressed within them. Listing shall not be taken as endorsement of any kind. We cannot guarantee that these links will work all of the time and we have no control over availability of the linked pages
Individual Handbook Chapters
The entire Data Requirements Handbook is also available as a single pdf file (pdf, 191 pages).
Chapter 1: Introduction (pdf, 8 pages)
Currently Contents list and details of updates only
Last update 01/10/09
Chapter 2: Guidance on Good Laboratory Practice (GLP) (pdf, 5 pages)
Last update 28/09/04
Chapter 3: Physical and Chemical properties (pdf, 62 pages)
Last update 28/09/04: Links updated to the Applicant Guide
Chapter 4: Toxicity (pdf, 8 pages)
Last update 28/09/04: Links updated to the Applicant Guide
Chapter 5: Residues (pdf, 4 pages)
Last update 01/10/05
Chapter 6: Environmental Fate and Behaviour (pdf, 41 pages)
Last update 24/03/06: Links to other guidance documents updated
Chapter 7: Ecotoxicology (pdf, 16 pages)
Last update 28/09/04: Links updated to the Applicant Guide
Chapter 8: Efficacy (pdf, 43 pages)
Last update 01/10/09: Multiple updates
Chapter 9: Humaneness Requirements (pdf, 2 pages)
Last update 23/05/01
Chapter 10: Glossary and Useful Addresses
Not Yet Available - 01/10/09
Supplementary guidance on data requirements
Additional guidance on specific areas not included in the Data Requirements Handbook.
- Efficacy guidelines
- Ecotox and Environmental fate guidelines
- Toxicity and Operator Exposure guidelines
- Crop Hierarchy (pdf, 15 pages)
Software Models
- UK Predictive Operator Exposure Model (UK POEM) (MS Excel)
- 91/414 packaging checklist guide (MS Word): This guide will also be available soon on the European Crop Protection Association (ECPA) website.
- Hard surfaces model (HardSPEC) for first tier estimation of herbicide exposure concentrations in surface and ground waters in the UK, resulting from product use on plant free areas. An associated research report also available.
- Spreadsheet to aid the calculation of ETE
- Proportion of different food types in the bird and mammal diet; PDcalc. PD, or the proportion of different food types in the bird and mammal diet, is one of the refinement steps discussed in the EU Guidance Document on Risk Assessment for Birds and Mammals under Council Directive 91/414/EEC (see SANCO/4145/2000) Guidance is provided in SANCO 4145/2000 on how to refine PD, however to assist in this refinement step, PSD (now CRD) has produced a spreadsheet to aid the calculation of proportion of different food types in the bird and mammal diet. There is an instruction page linked to this spreadsheet and it is strongly recommended that this is read before using the spreadsheet. It is also strongly recommended that the guidance document is read prior to using this spreadsheet.
CRD is not responsible for the accuracy or use of any endpoints derived using these models
Please refer to relevant sections of the Applicant Guide.